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KMID : 0608520100160030107
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Korean Journal of Oriental Medicine
2010 Volume.16 No. 3 p.107 ~ p.113
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Effects of the Korean Herbal Bathing Candidates on Skin Lesions in Mice Model
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Han Seung-Heon
Kim Jung-Soo
Jugn Bo-Kyoung
Park So-Jung
Kim Hyung-Woo
Chae Han
Kwon Young-Kyu
Kim Byung-Joo
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Abstract
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Objective:Active treatment for a skin condition has produced a substantial change in the history of allergic contact or wound induced dermatitis. The frequency of opportunistic contacts and allergen-related dermatitis has increased, though new skin treatments have developed. Especially, there has been a interest in the korean herbal bathing. This study was performed to investigate the effects of the korean herbal bathing candidates on skin lesions in mice model. These candidates are Korea"s representative herbs on skin lesions.
Method: ICR mice were divided into five groups : naive, control, experimental group A and B and C. Control and experimental groups induced skin lesions by DNFB and TMA. Each experimental group was pasted with corresponding korean herbal bathing candidates on skin lesions.
Result: Significant improvements in skin wound index, epidermal thickness associated with skin lesions were seen with the korean herbal bathing candidates.
Conclusion: These results suggest that the korean herbal bathing candidates could be at least as effective as steroid, anti-histamine for the treatment of skin lesions.
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KEYWORD
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Korean herbal bathing, Skin lesions, skin wound index, epidermal thickness
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